Diastology, 2nd Edition

Diastology, 2nd Edition

Descripcion del producto

ISBN Number 9780323640671
Main Author By Allan L. Klein, MD and Mario J. Garcia, MD, FACC
Copyright Year 2021
Edition Number 2
Format Book
Trim 276 x 216 (8 1/2 x 10 7/8)
Illustrations Approx. 400 illustrations (350 in full color)
Imprint Elsevier
Page Count 544
Publication Date 18 Nov 2020
Stock Status IN STOCK

Book Description


Accounting for more than 40% of all heart failure problems diastolic heart failure is a complex and often difficult diagnosis with rapidly evolving diagnostic management protocols. Diastology: Clinical Approach to Heart Failure with Preserved Ejection Fraction 2nd Edition brings you up to date and equips you to successfully diagnose and manage even the most challenging incidences of diastolic heart failure and their comorbidities. It incorporates the latest guidelines for the diagnostic evaluation of the patient with suspected or known diastolic dysfunction provides a comprehensive review of clinical conditions associated with heart failure with preserved ejection fraction and describes the complementary role of imaging modalities and novel therapeutic approaches.


Key Features
  • Keeps you current with recent extensive changes in the understanding of the mechanisms of diastolic heart failure with preserved ejection fraction (HFpEF) that have resulted in dramatic changes in treatment guidelines.
  • Covers the latest molecular, genetic, and cellular mechanisms behind diastolic heart failure as a basis for the latest clinical approaches, diagnosis, and treatment of common and uncommon pathological conditions such as hypertensive heart disease, cardiomyopathies, arterial and valvular diseases, pericardial diseases, congenital heart disease, diabetes mellitus, and metabolic syndrome.
  • Features 50 video cases, new key summary points, new multiple-choice review questions, and six new chapters: Evaluation of Diastolic Function by Radionuclide Techniques; Diastology Stress Test; ASE/EACVI Diastolic Guidelines; Valve Disease; Perioperative Assessment of Diastolic Dysfunction; and Pulmonary Hypertension.
  • Reviews new techniques and indices for assessing diastolic function, such as 3D echo, strain rate imaging, late gadolinium enhancement and T1-mapping by CMR, and novel nuclear scintigraphic methods ? as well as the traditional indices of LV filling, LA function, and tissue Doppler indices.
  • Covers emerging topics such as the role of neurohormones, global and regional systolic function of the left ventricle, chronotopic incompetence and pacing, aging, perioperative assessment, and more.
  • Presents information in a quick-retrieval format, covering Epidemiology, Pathophysiology, Diagnostic Evaluation, Differential Diagnosis, Treatment, and Future Directions.
  • Helps you learn efficiently and prepare for specialty board examination with key summaries and multiple-choice questions and answers for each chapter.
  • Enhanced
  • eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Author Information
By Allan L. Klein, MD, Department of Cardiovascular Medicine, The Cleveland Clinic, Cleveland, OH and Mario J. Garcia, MD, FACC, Director of Non-invasive Cardiac Imaging, Mount Siani School of Medicine, New York, NY

Book Contents


Part I: Basic Determinants of Diastolic Function

  1. Molecular, Gene, and Cellular Mechanis
  2. Pathophysiology of Heart Failure With a Preserved Ejection Fraction: Measurements and Mechanisms Causing Abnormal Diastolic Function
  3. Role of the Pericardium in Diastolic Dysfunction
  4. Left Atrial Function: Basic Physiology
  5. Physical Determinants of Diastolic Flow
  6. Ventricular?Arterial Interaction in Patients With Heart Failure and a Preserved Ejection Fraction
  7. Part II: Diagnosis of Heart Failure With Preserved Ejection Fraction

  8. General Principles, Clinical Definition, Epidemiology, and Pathophysiology
  9. Invasive Hemodynamic Assessment in Heart Failure With Preserved Ejection Fraction
  10. Two-Dimensional and Doppler Evaluation of Left Ventricular Filling, Including Pulmonary Venous Flow Velocity
  11. Evaluation of Diastolic Function by Tissue Doppler, Strain, and Torsion Analysis
  12. Color M-mode Doppler
  13. Assessment of Left Atrial Size and Function
  14. Evaluation of Intracardiac Filling Pressures
  15. Evaluation of Right Ventricular Diastolic Function
  16. Evaluation of Diastolic Function by Cardiac Magnetic Resonance Imaging
  17. Evaluation of Diastolic Function by Radionuclide Techniques
  18. Diastolic Echocardiographic Examination
  19. Diastology Stress Test
  20. ASE/EACVI Diastolic Guidelines: Strength and Limitations
  21. Part III: Cardiac Diseases With HFpEF

  22. Hypertension and Its Relation to Heart Failure With a Preserved Ejection Fraction
  23. Valve Disease
  24. Stage D Heart Failure With Preserved Ejection Fraction, Heart Transplantation, and Mechanical Circulatory Support
  25. Primary Restrictive, Infiltrative, and Storage Cardiomyopathies
  26. Coronary Artery Disease
  27. Hypertrophic Cardiomyopathy
  28. Pericardial Diseases: Constrictive Pericarditis and Pericardial Effusion
  29. Diastolic Function in Children and in Children With Congenital Heart Disease
  30. Diabetes Mellitus
  31. Part IV: Emerging Topics in HFpEF

  32. Global and Regional Systolic Function of the Left Ventricle
  33. Chronotropic Incompetence and Pacing in HPEF Heart Failure with Preserved Ejection Fraction
  34. Aging and Heart Failure With Preserved Ejection Fraction
  35. Perioperative Assessment of Diastolic Function
  36. Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction
  37. Part V: Treatment of HFpEF

  38. General Treatment of Heart Failure With Preserved Ejection Fraction and Randomized Trials
  39. Echo-Based Approach to the Management of Heart Failure With Preserved Ejection Fraction
  40. Future Therapies in HFpEF
  41. Part VI: Cases of Diastolic Heart Failure

  42. Cases of Diastolic Heart Failure